Assay ID | Title | Year | Journal | Article |
AID1528311 | Inhibition of mitochondrial oxidative phosphorylation in human DLD1 cells assessed as reduction in oxygen consumption rate by seahorse XFe96 analyser based assay | 2019 | Journal of medicinal chemistry, 12-26, Volume: 62, Issue:24
| An Underlying Mechanism of Dual Wnt Inhibition and AMPK Activation: Mitochondrial Uncouplers Masquerading as Wnt Inhibitors. |
AID1286336 | Increase in mitochondrial oxygen consumption in human HT-29 cells measured for 20 to 60 mins by time-resolved fluorescence assay | 2016 | Journal of natural products, Jan-22, Volume: 79, Issue:1
| Amorfrutin C Induces Apoptosis and Inhibits Proliferation in Colon Cancer Cells through Targeting Mitochondria. |
AID1286340 | Increase in extracellular acidification rate in human HT-29 cells measured for 20 to 150 mins by time-resolved fluorescence assay relative to control | 2016 | Journal of natural products, Jan-22, Volume: 79, Issue:1
| Amorfrutin C Induces Apoptosis and Inhibits Proliferation in Colon Cancer Cells through Targeting Mitochondria. |
AID1609720 | Inhibition of ubiquinol cytochrome c reductase in Leishmania donovani promastigotes mitochondria at 2 uM using decylubiquinol as substrate in presence of cytochrome c relative to control | 2019 | European journal of medicinal chemistry, Nov-15, Volume: 182 | β-Amino acid derivatives as mitochondrial complex III inhibitors of L. donovani: A promising chemotype targeting visceral leishmaniasis. |
AID1528308 | Activation of AMPK (unknown origin) assessed as increase in AMPK phosphorylation at T172 residue by Western blot analysis | 2019 | Journal of medicinal chemistry, 12-26, Volume: 62, Issue:24
| An Underlying Mechanism of Dual Wnt Inhibition and AMPK Activation: Mitochondrial Uncouplers Masquerading as Wnt Inhibitors. |
AID1528309 | Activation of AMPK (unknown origin) assessed as reduction in ACC phosphorylation at S79 residue by Western blot analysis | 2019 | Journal of medicinal chemistry, 12-26, Volume: 62, Issue:24
| An Underlying Mechanism of Dual Wnt Inhibition and AMPK Activation: Mitochondrial Uncouplers Masquerading as Wnt Inhibitors. |
AID1296008 | Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening | 2020 | SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1
| Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening. |
AID1347159 | Primary screen GU Rhodamine qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
AID1346987 | P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
AID1347160 | Primary screen NINDS Rhodamine qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
AID1346986 | P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
AID1801889 | Cytochrome b Enzyme Assay from Article 10.1016/j.chembiol.2016.06.016: \\A Fungal-Selective Cytochrome bc1 Inhibitor Impairs Virulence and Prevents the Evolution of Drug Resistance.\\ | 2016 | Cell chemical biology, 08-18, Volume: 23, Issue:8
| A Fungal-Selective Cytochrome bc |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |